硕导简介-薛宏坤

硕导简介——薛宏坤

一、个人简介

薛宏坤，男，1988年9月出生，博士，讲师，硕士研究生导师。

教育与工作经历：

2010年9月-2014年6月 东北农业大学，食品科学与工程，学士学位；

2014年9月-2019年6月 东北农业大学，硕博连读，农产品加工与贮藏博士学位；

2019年7月-2021年7月 清华大学，    博士后，功能性食品；

2021年10月-至今      河北大学中医学院任教。

联系方式：xuehk0906@hbu.edu.cn；13331200798

二、研究方向

研究方向：天然产物提取分离纯化及活性；功能性食品研发。

三、代表性论文

[1]Tan Jiaqi, Li Pengcheng, Wang Weili, Cai Xu, & Hongkun Xue*. Separation of gallic acid from Cornus officinalis and its interactions with corn starch[J]. International Journal of Biological Macromolecules, 2022, 208, 390-399. 

[2]Tan Jiaqi, Cui Pengshan, Ge Shaoqin, Cai Xu, Hongkun Xue*. Ultrasound assisted aqueous two-phase extraction of polysaccharides from Cornus officinalis fruit: Modeling, optimization, purification, and characterization[J]. Ultrasonics Sonochemistry, 2022, 84, 105966.

[3]Hongkun Xue, Jiaqi Tan, Qian Li, Jintian Tang, Xu Cai*. Counter-current fractionation-assisted and bioassay-guided separation of active compounds from cranberry and their interaction with α-glucosidase [J]. LWT - Food Science and Technology, 2021, 145, 111374.

[4]Wenli Wang, Jiaqi Tan, Lamu Nima, Yumei Sang, Xu Cai, Hongkun Xue*. Polysaccharides from fungi: A review on their extraction, purification, structural features, and biological activities [J]. Food Chemistry X, 2022, 15, 100414.

[5]Hongkun Xue, Jiaqi Xu, Jinling Zhang, Yaning Wei, Xu Cai, & Jiaqi Tan. (2022). Modeling, optimization, purification, and characterization of polysaccharides from lilium lancifolium thunb. LWT - Food Science and Technology, 2022, 162, 113491.

[6]Hongkun Xue, Xiaohan Zhu, Jiaqi Tan, Linlin Fan, Qian Li, Jintian Tang, Xu Cai*. Counter-current fractionation-assisted bioassay-guided separation of active compound from blueberry and the interaction between the active compound and α-glucosidase[J]. Foods, 2021, 10(3):509.

[7]Xu Cai, Mi Xiao, Hongkun Xue*. Extraction and separation of flavonoid from Malus hupehensis using high-speed countercurrent chromatography based on deep eutectic solvent[J]. Journal of Chromatography A, 2021, 1641, 461998.

[8]Hongkun Xue, Jiaqi Tan, Xu Cai*, et al. Ultrasound-assisted enzymatic extraction of anthocyanins from raspberry wine residues: Process optimization, structure, and antioxidant activity determination [J]. Food Analytical Methods, 2021, 1-8

[9]Hongkun Xue, Jiaqi Tan, Qian Li, Jintian Tang, Xu Cai*. Optimization ultrasound-assisted deep eutectic solvent extraction of anthocyanins from raspberry using response surface methodology coupled with genetic algorithm [J]. Foods, 2020, 9(10):1409.

[10]Xu Cai, Mi Xiao, Hongkun Xue*. Separation of six antioxidants from Hypsizygus marmoreus by high-speed countercurrent chromatography utilizing an approach based upon the polarity parameter model[J]. Journal of Chromatography A, 2020, 1633, 461650.

[11]Jiaqi Tan, Qian Li, Hongkun Xue*. Ultrasound-assisted enzymatic extraction of anthocyanins from grape skins: Optimization, identification, and antitumor activity [J]. Journal of Food Science, 2020, 85(11), 3731-3744.

四、代表性科研项目

（1）河北大学高层次人才科研启动项目，《海棠多糖改善胰岛素抵抗的构效关系及其作用机制研究》，经费50.0万，2021.11-2.24.11，在研，主持。

（2）主持第67批次中国博士后科学基金面上资助项目，经费8.0万元，2019-2021。

（3）主持冷链生物医药制品全程温度监控（日本-丰田-清华大学联合基金-300万）。

（4）作为主要参与人开展两项国家自然科学基金面上资助项目。

五、出版教材、授权/申请专利

（1）参与编写《体腔热灌注治疗》，人民卫生出版社。

（2）申请发明专利以下两项：

[1]一种用于高粘度果浆铺料厚度可控装置（201710442767.3）